Selebi Phikwe evolved from a mining town into alternative sectors, including logistics and coal-based chemicals. The existing smelting facilities are being used for base metal beneficiation, relying on the availability of raw material supplies from the region.

Apart from these sectors, Selebi Phikwe is well populated by tourism-related industries and activities such as a casino, golf courses, sports clubs, bird watching and more. There are also plenty of hotels, guest houses, camping sites and lodges available as tourist accommodation in the area.